Efficacy of dabrafenib/trametinib in pancreatic ductal adenocarcinoma with braf nvtap deletion: a case report

HIGHLIGHTS

  • who: Ji Eun Shin and colleagues from the United States University of Verona, Italy have published the Article: Efficacy of dabrafenib/trametinib in pancreatic ductal adenocarcinoma with BRAF NVTAP deletion: A case report, in the Journal: (JOURNAL)

SUMMARY

    PDAC is one of the most lethal diseases, with the 5-year survival rate remaining as low as 6% in the USA. As mentioned above, BRAF NVTAP deletion is reported as an oncogenic mutation in PDAC. There was a single previous case where dabrafenib was used to target BRAF NVTAP deletion, and the clinical effectiveness . . .

     

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