HIGHLIGHTS
- What: The aim of this study was to perform a systematic review of the existing evidence base, to identify and appraise the effectiveness of periodontal prevention and treatment modalities in individuals diagnosed with DS and to determine the estimates of the effects of implemented periodontal prevention and treatment strategies compared to chromosomally normal (CN) individuals. This systematic review was conducted and reported in conformity with the Cochrane Handbook of Systematic Reviews of Interventions21 and followed the Prefered Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines22. The primary focus was on mean PD while other periodontal . . .
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