Efficient access to general α-tertiary amines via water-accelerated organocatalytic multicomponent allylation

HIGHLIGHTS

  • who: Prithwish Goswami from the Sungkyunkwan University have published the article: Efficient access to general u03b1-tertiary amines via water-accelerated organocatalytic multicomponent allylation, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • how: A detailed condition optimization study of the reaction medium was conducted the results are shown in Fig 2a. The authors then decided to employ a water-rich reaction medium for this allylation reaction. The summarized results were obtained by reacting ketones (1a and 10h) with a wide variety of amines (2a-2n).

SUMMARY

    As a model reaction, the authors . . .

     

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