Efficient aqueous remote loading of peptides in poly(lactic-co-glycolic acid)

HIGHLIGHTS

• who: Morgan B. Giles from the the Biointerfaces Institute University of Michigan, Bonisteel Blvd, Ann Arbor, MI, USA have published the paper: Efficient aqueous remote loading of peptides in poly(lactic-co-glycolic acid), in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 16/05/2022

SUMMARY

The authors discovered that two of the peptides currently used in commercial PLGA long-acting release depots (LARs), leuprolide and octreotide, long known to bind to the surface of uncapped PLGA (PLGA-COOH), can in fact be absorbed rapidly into the polymer phase of PLGA-COOH at . . .

 



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