HIGHLIGHTS
- who: Karen S Harris from the Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia, Division of have published the Article: Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 18/Dec/2015
- what: The authors report the identification of four asparaginyl endopeptidases (AEPs) proteases implicated in cyclization from the cyclotide-producing plant Oldenlandia affinis. The authors demonstrate the broad utility of this enzyme by cyclization of peptides unrelated to cyclotides. The authors propose that recombinant OaAEP1b . . .
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