Efficient biosynthesis of pinosylvin from lignin-derived cinnamic acid by metabolic engineering of escherichia coli

HIGHLIGHTS

  • who: Yueli Hu from the Laboratory have published the Article: Efficient biosynthesis of pinosylvin from lignin-derived cinnamic acid by metabolic engineering of Escherichia coli, in the Journal: (JOURNAL)
  • what: The aim of this work was to engineer E. coli for the production of pinosylvin from trans-cinnamic acid with both high titre and high yield.
  • how: For the above reasons the authors selected u00adPsSTS2Q361R PpSTS and PtSTS as candidates for pinosylvin synthases for further study. The above results indicated that in the absence of cerulenin insufficient levels of malonyl-CoA block pinosylvin . . .

     

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