Efficient deformation mechanisms enable invasive cancer cells to migrate faster in 3d collagen networks

HIGHLIGHTS

  • who: Laure Laforgue from the Univ have published the article: Efficient deformation mechanisms enable invasive cancer cells to migrate faster in 3D collagen networks, in the Journal: Scientific Reports Scientific Reports of 30/Nov/2021
  • what: The authors investigated how the malignancy of bladder cancer cells is related to their migration strategy in 3D collagen matrices mimicking physiological environments. The study revealed that grade-3 cells (T24 and J82 cells) were characterized by a great diversity of shapes in comparison to grade-2 cells (RT112 cells).
  • how: To relate the largest fiber-displacements . . .

     

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