Efficient dna fluorescence labeling via base excision trapping

HIGHLIGHTS

• who: Yong Woong Jun from the (UNIVERSITY) have published the research work: Efficient DNA fluorescence labeling via base excision trapping, in the Journal: (JOURNAL)
• what: The authors report an in situ DNA labeling strategy for oligonucleotides as well as dsDNA that makes use of aldehyde-reactive rotor dyes, also known as universal base excision reporters (UBER)9, 10, to trap AP sites resulting from excision of deaminated DNA bases.
• how: The results showed that all four uracils were replaced with CCVJ-1 in the ODN leaving negligible amounts of under-labeled ODN thus . . .
  

   

  

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