HIGHLIGHTS
- who: Aran F. Labrijn from the Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense have published the research work: Efficient Generation of Bispecific Murine Antibodies for Pre-Clinical Investigations in Syngeneic Rodent Models, in the Journal: Scientific Reports Scientific Reports of 19/04/2017
- what: The authors show that the optimized combinations of matched point-mutations enabled efficient generation of murine bsAbs for all subclasses studied (mouse IgG2a and IgG2b; rat IgG2a IgG2b and IgG2c). The analysis showed comparable PK profiles and no significant differences in the clearance rates, indicating . . .
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