Efficient t cell migration and activation require l-plastin

HIGHLIGHTS

  • who: Hemant Joshi from the Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, StLouis, MO, United StLouis, MO, United States have published the research work: Efficient T Cell Migration and Activation Require L-Plastin, in the Journal: (JOURNAL)
  • future: Detailed molecular studies are required to resolve the disparities of LPL regulation in human and mouse T_cells. Conformation-specific binding of LPL to LFA-1 (CD11a/CD18) in T_cells is unresolved and future studies will address this important open question. Studies are required to determine how signals from the multiple regulatory sites . . .

     

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