Efficient utilization of 6-aminouracil to synthesize fused and related heterocyclic compounds and their evaluation as prostate cytotoxic agents with cathepsin b inhibition

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  • who: Marwa Taha Mostafa Sarg and Shereen Said El-Shaer from the Department of Organic Chemistry, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt have published the research work: Efficient Utilization of 6-Aminouracil to Synthesize Fused and Related Heterocyclic Compounds and Their Evaluation as Prostate Cytotoxic Agents with Cathepsin B Inhibition, in the Journal: (JOURNAL)
  • what: No IC50 (u03bcM) 0.1 Doxorubicin Aligned with the aim of this work; to synthesize and study the effect of various heterocyclic rings upon attachment to C6 position or fusion to the uracil backbone, the IC50 of . . .

     

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