Egfr as a prognostic biomarker and therapeutic target in ovarian cancer: evaluation of patient cohort and literature

HIGHLIGHTS

  • who: Top from the Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA have published the article: EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: evaluation of patient cohort and literature, in the Journal: (JOURNAL)
  • how: The authors analyzed EGFR staining in the patient cohort via multiple approaches.
  • future: Future studies should pursue other staining methods or analysis in combination with other pathway mediators.

SUMMARY

    Unfortunately, response to EGFR-targeted tyrosine kinase-based inhibitors (TKIs) in unselected ovarian cancer patient populations has not been encouraging, with . . .

     

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