Egfr-targeted bacteriophage lambda penetrates model stromal and colorectal carcinoma tissues, is taken up into carcinoma cells, and interferes with 3-dimensional tumor formation

HIGHLIGHTS

  • who: Haein Huh and collaborators from the University, China have published the article: EGFR-targeted bacteriophage lambda penetrates model stromal and colorectal carcinoma tissues, is taken up into carcinoma cells, and interferes with 3-dimensional tumor formation, in the Journal: (JOURNAL)
  • what: Given the substantial advantages of phage technology for the design of novel therapeutics the authors investigate the use of engineered bacteriophages in cancer therapeutic applications.
  • how: The authors investigated phage access in these 3dimensional tissue models of the CRC stroma and parenchyma with l phage both unmodified and with epidermal growth . . .

     

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