Eight gene mutation-based polygenic hazard score as a potential predictor for immune checkpoint inhibitor therapy outcome in metastatic melanoma

HIGHLIGHTS

• who: . and collaborators from the General Hospital, China University of Traditional have published the research: Eight gene mutation-based polygenic hazard score as a potential predictor for immune checkpoint inhibitor therapy outcome in metastatic melanoma, in the Journal: (JOURNAL)
• what: As reported, the 21 gene model in breast cancer prognostic prediction could effectively assess the recurrence risk and help treatment decision-making (Varga et_al, 2019); it was reasonable to speculate that the polygenic mutation model might be effective to predict the ICI therapy outcomes.
• how: The authors developed this PHS model to predict . . .
  

   

  

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