Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model

HIGHLIGHTS

• who: Jennifer E. Hundt from the University of Genoa, Italy have published the article: Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model, in the Journal: (JOURNAL)
• what: The authors conclude that, although the model has only bispecific anti-DSG1/DSG3 scFv, some ultrastructural hallmarks of desmosome morphology following Px4-3 binding are reproduced in the HSOC model, reflecting the lesional skin of pemphigus patients.
• how: To obtain additional insights into the mechanisms of how Px4-3 induces split formation the authors evaluated the ultrastructural morphology of desmossomal dissociation . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.