Elevated csf levels of tace activity and soluble tnf receptors in subjects with mild cognitive impairment and patients with alzheimer ’ s disease

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  • who: ADAM- et al. from the CSF samples were obtained from total , patients in two independent clinical research center: the Alzheimer Memorial Center, Department of Psychiatry, LudwigMaximilian University in Germany and the Department of Clinical Neuroscience, University of Goteborg, Sahlgren's University Hospital, SwedenA total of , individuals were recruited from the above centers, probable AD patients, MCI subjects and , agematched healthy individuals. As we described previously [18, ], diagnosis of AD was made according to the National Institute of Neurological and Communicative Disorders and Stroke (NINCDS-ADRDA) criteria [20], including the Mini-Mental State Examination (MMSE) and MCI . . .

     

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