HIGHLIGHTS
- who: Zhaorui Miao from the Department of Pathology and Pathophysiology, Department Zhejiang University School of Medicine, Hangzhou, China have published the research: Elevated transcription and glycosylation of B3GNT5 promotes breast cancer aggressiveness, in the Journal: (JOURNAL)
- what: The authors showed that B3GNT5 copy number amplification and hypomethylation of B3GNT5 promoter contributed to overexpression of B3GNT5 in BLBC. The analysis showed that patients with high expression of B3GNT5 had shorter overall survival (OS), relapse-free survival (RFS) and distant metastasis-free survival (DMFS) (Fig 5 H and Figure S5C). The study showed that B3GNT5 enhanced CSCs . . .
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