Elk1-induced upregulation of long non-coding tnk2-as1 promotes the progression of acute myeloid leukemia by ezh2-mediated epigenetic silencing of celf2

HIGHLIGHTS

  • who: LncRNA TNK and collaborators from the The First Affiliated Hospital of Henan University of Science and Technology have published the research work: ELK1-induced upregulation of long non-coding TNK2-AS1 promotes the progression of acute myeloid leukemia by EZH2-mediated epigenetic silencing of CELF2, in the Journal: (JOURNAL)
  • what: Our results revealed that TNK2-AS1 was remarkably upregulated in AML patients and partly activated by ELK1.
  • how: Tumor xenografts All animal care and experiments were carried out in accordance with the guidance of the National Institutes of Health and approved by . . .

     

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