Ellagic acid improves benign prostate hyperplasia by regulating androgen signaling and stat3

HIGHLIGHTS

• who: Woo Yong Park from the patients [27]Emerging data have shown that pro-inflammatory cytokines, including , and , secreted by these inflammatory cells, selectively promote the proliferation of prostate epithelial cells [26, ]. Other studies have confirmed that epithelial and stromal cells, as well as infiltrated immune cells, have cytokine receptors on their membrane surface and can participate in local prostate inflammatory microenvironments [29]. Our findings showed that TP increased pro-inflammatory mediators such as , and TNF-u03b1 in prostate tissue and , prostate epithelial cells. Moreover, EA significantly reduced the expression of , and TNF-u03b1 through inhibition of . . .
  

   

  

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