Elucidating the importance and regulation of key enhancers for human meis1 expression

HIGHLIGHTS

  • who: Ping Xiang from the (UNIVERSITY) have published the Article: Elucidating the importance and regulation of key enhancers for human MEIS1 expression, in the Journal: (JOURNAL) of 27/05/2022
  • what: The authors present a comprehensive functional analysis of the locus-wide regulatory regions of the human MEIS1 gene in the U937 AML cell line.
  • how: The authors utilized the Cherry colored lentiviral CRISPR-Cas9 mediated genome editing vector system (Supplementary Fig S2) in the mono-allelic MEIS1-GFP-tagged U937 cells. The authors hypothesized that binding_sites of some critical regulators of MEIS1 . . .

     

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