Emerging role of different dna methyltransferases in the pathogenesis of cancer

HIGHLIGHTS

  • who: August and collaborators from the Institute of Health and Medical Science (CAS), China of Texas Health Science have published the article: Emerging role of different DNA methyltransferases in the pathogenesis of cancer, in the Journal: (JOURNAL)
  • what: Recent evidence has suggested a close link between DNMTs and the tumors' pathogenesis, throughout tumor invasion, proliferation, metastasis, diagnosis, and prognosis.
  • how: This study revealed that the DNMT1 expression level was all elevated from the PDAC models the Kras p53R172H tissues and Kras p53R172H cell line compared to the normal group (Godfrey et_al 2018). After . . .

     

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