Emerging role of lncrnas in drug resistance mechanisms in head and neck squamous cell carcinoma

HIGHLIGHTS

  • who: José A. Peña-Flores from the University of Alabama at Birmingham, United States have published the paper: Emerging role of lncRNAs in drug resistance mechanisms in head and neck squamous cell carcinoma, in the Journal: (JOURNAL)
  • what: In recent years, the pivotal role of lncRNAs in DR has begun to gain importance in the mechanisms that harbor and promote chemoresistance in HNSCC.
  • how: In another study the results showed that CAF-secreted midkine enhanced OSCC resistance to cisplatin by inducing ANRIL expression and increasing the antiapoptotic protein Bcl-2 expression .
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