Emerging role of mesenchymal stem cell-derived extracellular vesicles in oral and craniomaxillofacial tissue regenerative medicine

HIGHLIGHTS

  • who: . and collaborators from the Shanxi Medical University, China have published the paper: Emerging role of mesenchymal stem cell-derived extracellular vesicles in oral and craniomaxillofacial tissue regenerative medicine, in the Journal: (JOURNAL)
  • what: The major goal in immunomodulation is to transform macrophage phenotype from pro-inflammatory M1 to anti-inflammatory M2 by regulating the microenvironment, such as miR-146 and miR34 (Jiang et_al, 2012; Domenis et_al, 2018).
  • how: The results showed that EVs isolated from odontogenic conditioned medium up-regulated DSP dmp-1 ALP and Runx2 proteins to induce odontogenic differentiation of . . .

     

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