Emerging therapeutic targets for portal hypertension

HIGHLIGHTS

  • who: Eric Felli from the Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland have published the article: Emerging Therapeutic Targets for Portal Hypertension, in the Journal: (JOURNAL)
  • what: Knowledge of the PH mechanism underwent continuous development since the concept of splanchnic vasodilation contributing to increase portal pressure was introduced in the 1980s, providing for the first time a rationale for using splanchnic vasoconstrictors for the complications of PH.
  • future: Clinical studies suggest that lanifibranor may promote fibrosis regression in patients with NASH although further studies are . . .

     

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