Enabling allogeneic t cell-based therapies: scalable stirred-tank bioreactor mediated manufacturing

HIGHLIGHTS

  • who: Inbar Friedrich Ben-Nun from the Cell and Gene Therapy Research and Development, Lonza Inc, Rockville, MD, United States University of Chile, Chile have published the research work: Enabling Allogeneic T Cell-Based Therapies: Scalable Stirred-Tank Bioreactor Mediated Manufacturing, in the Journal: (JOURNAL)
  • what: In Figure 3A, the authors show that the CD4:CD8 T_cell ratio is maintained in the STR over 14 days of expansion, suggesting a 1:1 seeding ratio would be maintained by harvest. The authors show that T_cell expansion in the tested conditions resulted in the final T_cell subtype . . .

     

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