Endocrine disrupting chemicals in polycystic ovary syndrome: the relevant role of the theca and granulosa cells in the pathogenesis of the ovarian dysfunction

HIGHLIGHTS

  • who: Malgorzata Jozkowiak and colleagues from the Department of Toxicology, Poznan University of Medical Sciences, Dojazd, Poznan, Poland have published the research work: Endocrine Disrupting Chemicals in Polycystic Ovary Syndrome: The Relevant Role of the Theca and Granulosa Cells in the Pathogenesis of the Ovarian Dysfunction, in the Journal: Cells 2023, 174 of /2023/
  • what: This study has indicated increased testosterone synthesis and mRNA expression of 17u03b1-hydroxylase (P450c17) and cholesterol side-chain cleavage enzyme (P450scc) in theca-interstitial cells, which are suggested to be key features associated with PCOS pathogenesis. The studies have indicated . . .

     

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