Endocytosis in the axon initial segment maintains neuronal polarity

HIGHLIGHTS

• who: Kelsie Eichel from the (UNIVERSITY) have published the research: Endocytosis in the axon initial segment maintains neuronal polarity, in the Journal: (JOURNAL) of 11/05/2021
• what: The authors focused on an axonally polarized receptor and diverse dendritic receptors across multiple neuron types and species. The authors propose a mechanism in which axonally and dendritically polarized transmembrane_proteins enter the AIS through lateral diffusion, are captured for endocytosis, internalized from the plasma_membrane, and targeted for degradation (Fig 4n).
• how: Evidence of an AIS in C. elegans To investigate AIS function in neuronal polarity . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.