Endogenous bok is stable at the endoplasmic reticulum membrane and does not mediate proteasome inhibitor-induced apoptosis

HIGHLIGHTS

• who: Abbreviations Bok et al. from the Institute of Neuroscience (CNR), Italy University of Bern, Switzerland have published the paper: Endogenous Bok is stable at the endoplasmic reticulum membrane and does not mediate proteasome inhibitor-induced apoptosis, in the Journal: (JOURNAL)
• what: The authors report that under standard conditions, endogenous Bok is present at readily-detectable levels in key cultured cell lines, that its levels are not governed by the UPP, and that it does not mediate proteasome inhibitor-induced apoptosis. While the authors show that exogenous, over-expressed Bok can induce apoptosis, the authors . . .
  

   

  

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