HIGHLIGHTS
- who: ufeffJennyufeff ufeffLozada Ortizufeff from the Ruhr University Bochum, Germany have published the research work: Endoplasmic reticulum stress and ubiquitin-proteasome system impairment in natural scrapie, in the Journal: (JOURNAL)
- what: The aim of the UPR is to assist in the refolding of these misfolded proteins, and participate in their degradation through the endoplasmic_reticulum associated degradation (ERAD) mechanism, which is the principal ER quality_control machinery that recognizes unfolded proteins and relocates them to the cytosol to be degraded by the ubiquitin-proteasome system to maintain homeostasis (Hwang and Qi, 2018). The aim of this study . . .
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