Endothelial cell cycle state determines propensity for arterial-venous fate

HIGHLIGHTS

  • who: Nicholas W. Chavkin from the Mouse strains All animal procedures were approved by the Institute for Animal Care and Use Committees at Yale University and the University of VirginiaAnimal housing was controlled by Yale and University of Virginia Vivarium Staff, maintaining a , h light to , h dark cycle, an ambient temperature of, ., u00b0C (acceptable range, u00b0C), and an ambient humidity, % (acceptable range, %). In this study, R FUCCI2aR mice, were bred with Cdh5-Cre, mice, to generate endothelialspecific FUCCI expression after tamoxifen injection. Tamoxifen (Sigma Cat#, ) was resuspended in, % EtOH and, % Corn oil (Sigma Cat#, ) at , mg . . .

     

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