Endothelial cell protein targeting by myeloperoxidase-derived 2-chlorofatty aldehyde

HIGHLIGHTS

  • who: Shubha Shakya et al. from the Center for Cardiovascular Research, Saint Louis University School of Medicine, StLouis, MO, USA have published the article: Endothelial Cell Protein Targeting by Myeloperoxidase-Derived 2-Chlorofatty Aldehyde, in the Journal: Antioxidants 2022, 11, x FOR PEER REVIEW of 25/Oct/2017
  • what: The authors investigate protein modification specifically by 2-ClFALD under non-reducing conditions (e_g without stabilizing Schiff base bonds) which likely reflects nucleophilic targeting of the electrophilic chlorinated carbon. The authors investigated protein modification by 2-ClHDA in the absence of reduction, the conversion of 2 . . .

     

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