Endothelial kca channels: novel targets to reduce atherosclerosis-driven vascular dysfunction

HIGHLIGHTS

  • who: March and colleagues from the University of Wollongong, Australia have published the research work: Endothelial KCa channels: Novel targets to reduce atherosclerosis-driven vascular dysfunction, in the Journal: (JOURNAL)
  • what: These observed changes were accompanied by a reduction in KCa3.1 mRNA Thus, BZs provide a clear precedent and rationale for how agonistic agents that facilitate the activity of key molecules can be used to strengthen intrinsic signaling pathways and boost functional outcomes.
  • future: Studies thus far suggest that facilitation of KCa2.X/ KCa3.1 activity in_vivo by a positive modulator is . . .

     

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