HIGHLIGHTS
- who: Florence Ho from the DepartmentMonash University have published the research work: Endothelial reactive oxygen-forming NADPH oxidase 5 is a possible player in diabetic aortic aneurysm but not atherosclerosis, in the Journal: Scientific Reports Scientific Reports
- what: Whilst the model has the limitation of only mimicking physiological human expression of Nox5 in endothelial cells, the Nox5 KO rabbit model is based entirely on endogenous expression levels and localization. The study has limitations as the downstream mechanisms of Nox5 aggravating diabetic aneurysm remain unclear.
- how: These data indicated that endothelial expression of Nox5 . . .
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