HIGHLIGHTS
- who: Tadanori Mammoto and Akiko Mammoto from the University of California, Davis, United States have published the paper: Endothelial senescence mediates hypoxia-induced vascular remodeling by modulating PDGFB expression, in the Journal: (JOURNAL)
- what: Although there is no direct link between TWIST1 and PDGFB in the IPA interactome of senescence/SASP related genes, endothelial senescence may control vascular remodeling in PH through TWIST1-PDGFB signaling, and the authors focused on this signaling in this study.
- how: The in_vivo animal study was carried out in strict accordance with the recommendations in the Guide for . . .
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