Endothelial-to-mesenchymal transition in atherosclerosis: friend or foe?

HIGHLIGHTS

• who: Sarin Gole and collaborators from the Cleveland, OH, USA have published the research: Endothelial-to-Mesenchymal Transition in Atherosclerosis: Friend or Foe?, in the Journal: Cells 2022, 2946 of 21/09/2022
• what: Simons et_al have shown that reduced EndoMT marker expression due to EC-specific + cells within the atherosclerotic lesion fiu2010 EndoMT knockout is an important source of ACTA2occlusion Tgfbr1/Tgfbr2 resulted in decreased and regression of plaques [13]. brous cap.
• future: More studies are also needed to determine how EndoMT might be therapeutically manipulated to increase plaque stability without inducing . . .
  

   

  

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