Engineered adipose-derived stem cells overexpressing rxfp1 via crispr activation ameliorate erectile dysfunction in diabetic rats

HIGHLIGHTS

  • who: Taotao Sun and colleagues from the Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China have published the research: Engineered Adipose-Derived Stem Cells Overexpressing RXFP1 via CRISPR Activation Ameliorate Erectile Dysfunction in Diabetic Rats, in the Journal: Antioxidants 2023, 171 of /2023/
  • what: The authors aimed to increase the therapeutic effect of DMED by overexpressing the relaxin family peptide receptor 1 (RXFP1) using a clustered regularly interspaced short palindromic repeats activation (CRISPRa) system in ADSCs. The experiment showed that the number of erections was lowest in . . .

     

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