Engineered cell differentiation and sexual reproduction in probiotic and mating yeasts

HIGHLIGHTS

  • who: Emil D. Jensen from the (UNIVERSITY) have published the Article: Engineered cell differentiation and sexual reproduction in probiotic and mating yeasts, in the Journal: (JOURNAL) of 19/03/2022
  • what: The authors report transcriptome profiles following mating pathway activation in native and hGPCR-signaling yeast and use a model-guided approach to correlate gene_expression to morphological changes. The authors demonstrate mating between haploid cells armed with hGPCRs and endogenous biosynthesis of their cognate ligands. As measures of sexual reproduction between engineered haploid cells, the authors report both population-wise diploid frequencies and calculated mating . . .

     

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