Engineered neutral phosphorous dendrimers protect mouse cortical neurons and brain organoids from excitotoxic death

HIGHLIGHTS

• who: Inmaculada Posadas et al. from the Unidad Asociada Neurodeath, Facultad de Medicina, Universidad de Castilla-La Mancha, Centro de Investigaciu00f3n Biomu00e9dica en Red (CIBER), Instituto de Salud Carlos III (ISCIII), Madrid, Spain have published the article: Engineered Neutral Phosphorous Dendrimers Protect Mouse Cortical Neurons and Brain Organoids from Excitotoxic Death, in the Journal: (JOURNAL) of July/18,/2017
• what: Since the aza-bisphosphonate-terminated neutral phosphorous dendrimers used 9 of 16 in this work have shown anti-inflammatory properties both in_vitro and in_vivo by preventing NF-u03baB translocation to the cell nucleus , and neuroinflammation . . .
  

   

  

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