Engineering a two-gene system to operate as a highly sensitive biosensor or a sharp switch upon induction with β-estradiol

HIGHLIGHTS

• who: Tian Zhou from the SchoolTianjin University have published the article: Engineering a two-gene system to operate as a highly sensitive biosensor or a sharp switch upon induction with u03b2-estradiol, in the Journal: Scientific Reports Scientific Reports
• what: The authors propose a general way to assess the performance of a u03b2-estradiol biosensor. The authors focused on a set of synthetic activators where the bacterial LexA had the function of DBD and it was fused to HBD(hER) and an AD of viral, bacterial, or even mammalian origin. In the analysis , the best . . .
  

   

  

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