Engineering of a fully human anti-muc-16 antibody and evaluation as a pet imaging agent

HIGHLIGHTS

  • who: Hanan Babeker and collaborators from the Department of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK S N , Canada have published the research: Engineering of a Fully Human Anti-MUC-16 Antibody and Evaluation as a PET Imaging Agent, in the Journal: Pharmaceutics 2022, 2824 of /2022/
  • what: The authors seek to develop radiopharmaceuticals targeting the overexpression of biomarker, MUC16 (CA125), which is commonly overexpressed in ~80% of EOC and ~65% of PDAC. The authors report for the first time the development of a fully human monoclonal anti-MUC16 antibody . . .

     

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