Engineering of global transcription factor frur to redirect the carbon flow in escherichia coli for enhancing l-phenylalanine biosynthesis

HIGHLIGHTS

  • who: Minliang Chen from the (UNIVERSITY) have published the research: Engineering of global transcription factor FruR to redirect the carbon flow in Escherichia coli for enhancing l-phenylalanine biosynthesis, in the Journal: (JOURNAL)
  • what: FruR is a dual transcriptional regulator and it modulates the direction of carbon flow by transcriptional activation of genes encoding enzymes concerned with the Krebs cycle and the glyoxylate shunt and by repression of those genes that are involved in the glycolytic and Entner-Doudoroff (ED) pathways .
  • how: Sequencing results showed that there are 8 different types of FruR . . .

     

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