HIGHLIGHTS
- who: Jia Li from the (UNIVERSITY) have published the Article: Engineering of NEMO as calcium indicators with large dynamics and high sensitivity, in the Journal: (JOURNAL) of 16/03/2023
- what: The authors report herein the development of a suite of calcium sensors, designated NEMO, with fast kinetics and wide dynamic ranges (>100-fold).
SUMMARY
Compared with GCaMP6s, NEMOs could detect single action potentials in neurons with a peak SBR two times higher and a median peak SBR four times larger in_vivo, thereby outperforming most existing state-of-the-art GECIs . . .
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