Engineering strategies to enhance tcr-based adoptive t cell therapy

HIGHLIGHTS

  • who: Jan A. Rath and Caroline Arber from the Department of oncology UNIL CHUV, Ludwig Institute for Cancer Research Lausanne, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland have published the article: Engineering Strategies to Enhance TCR-Based Adoptive T Cell Therapy, in the Journal: Cells 2020, 9, 1485 of /2020/
  • what: The authors discuss how synthetic biology and innovative engineering strategies are poised to provide solutions for overcoming current limitations that include functional avidity and most importantly the tumor microenvironment.

SUMMARY

    Adoptive T_cell therapy (ACT) with T_cells expressing native . . .

     

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