Engineering synthetic lipopeptide antigen for specific detection of mycobacterium avium subsp. paratuberculosis infection

HIGHLIGHTS

  • who: Sylvie Bay and Franck Biet from the Austral University of Chile, Chile Agrario, Spain have published the research: Engineering Synthetic Lipopeptide Antigen for Specific Detection of Mycobacterium avium subsp. paratuberculosis Infection, in the Journal: (JOURNAL)
  • what: The authors produced, by chemical synthesis, a hydrosoluble variant of L5P termed L5P-Aqueous (L5P-Aq) and evaluated these compounds for the serological diagnosis of MAP from well-defined serum banks.
  • how: As discussed in detail below this result is likely due to the minor lipopeptide differences present in the cell walls of sheep vs. cattle . . .

     

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