Enhanced anticancer activity of 5’-dfur-pcl-mpeg polymeric prodrug micelles encapsulating chemotherapeutic drugs

HIGHLIGHTS

  • who: Alicia J. Sawdon and collaborators from the Department of Chemical Engineering, Michigan Technological University, Houghton, MI, USA have published the research work: Enhanced Anticancer Activity of 5’-DFUR-PCL-MPEG Polymeric Prodrug Micelles Encapsulating Chemotherapeutic Drugs, in the Journal: (JOURNAL)
  • what: The results of this study show that amphiphilic copolymer 5'-DFUR-PCL-MPEG was successfully synthesized and characterized, andshow its polymeric micelles were fabricated5'-DFUR-PCL-MPEG and analyzed.
  • how: The results indicated that TP expression and activity in HT-29 cells are high enough to convert 5-FU from loaded . . .

     

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