Enhanced flux prediction by integrating relative expression and relative metabolite abundance into thermodynamically consistent metabolic models

HIGHLIGHTS

• who: Vikash Pandey and colleagues from the Laboratory of Computational Systems Biotechnology, EPFL, Lausanne, Switzerland have published the paper: Enhanced flux prediction by integrating relative expression and relative metabolite abundance into thermodynamically consistent metabolic models, in the Journal: (JOURNAL) of May/13,/2019
• what: The authors demonstrate that REMI's ability to integrate different layers of constrictive data significantly reduces the solution space of feasible fluxes. REMI-Gex vs REMI-TGex: Flux variability analysis to investigate the influence of thermodynamic constraints To study the effect of thermodynamics on the model, the authors compared the reduction . . .
  

   

  

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