Enhanced il-1#_#x03b2; production is mediated by a tlr2-myd88-nlrp3 signaling axis during coinfection with influenza a virus and streptococcus pneumoniae

HIGHLIGHTS

• who: Angeline E. Rodriguez et al. from the Department of Biology, Missouri State University, Springfield, Missouri, United States of America have published the article: Enhanced IL-1#_#x03B2; production is mediated by a TLR2-MYD88-NLRP3 signaling axis during coinfection with influenza A virus and Streptococcus pneumoniae, in the Journal: PLOS ONE | https://doi.org/10.1371/journal.pone [0212236]. February 22, 2019 of /1371/
• what: The authors report the inflammasome is the major inflammasome regulating IL-1u03b2 activation during coinfection. The authors demonstrate that Nlrp3-/- mice or macrophages release less IL-1u03b2 than . . .
  

   

  

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