HIGHLIGHTS
- who: Tsung-Lang Chiu et al. from the Division of Neurosurgery, Neuro-Medical Scientific Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan School of Medicine, Tzu Chi University, Hualien, Taiwan have published the paper: Enhanced IRE1 Phosphorylation/Oligomerization-Triggered XBP1 Splicing Contributes to Parkin-Mediated Prevention of SH-SY5Y Cell Death under Nitrosative Stress, in the Journal: (JOURNAL)
- what: The authors demonstrate that IRE1u03b1/XBP1 signaling is specifically enhanced by WT parkin overexpression in response to an NO challenge. The authors provide the first demonstration that parkin facilitates the IRE1u03b1-triggered . . .
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