Enhanced therapeutic effect of optimized melittin-dkla, a peptide agent targeting m2-like tumor-associated macrophages in triple-negative breast cancer

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  • who: Soyoung Kim et al. from the Department of Physiology, College of Korean Medicine, Kyung Hee University, Kyungheedae-ro, Dongdaemun-gu, Seoul, Republic of Korea have published the research: Enhanced Therapeutic Effect of Optimized Melittin-dKLA, a Peptide Agent Targeting M2-like Tumor-Associated Macrophages in Triple-Negative Breast Cancer, in the Journal: (JOURNAL)
  • what: To increase the stability of the peptide fragment was conjugated with PEGylation at the amino terminus and was named This final drug candidate was assessed in vivo in a murine TNBC model and showed superior effects on tumor growth survival . . .

     

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