Enhanced therapeutic window for antimicrobial pept-ins by investigating their structure-activity relationship

HIGHLIGHTS

• who: Guiqin Wu and collaborators from the Editor: Wvan, University of have published the research work: Enhanced therapeutic window for antimicrobial Pept-ins by investigating their structure-activity relationship, in the Journal: PLOS ONE of 29/08/2022
• what: The authors focused on previously identified Pept-in P2 to investigate Pept-in structure and activity relationship due to its thoroughly investigated mode of action in_vitro and efficacy in reducing bacterial load in a mouse model infected with E. coli.
• how: Next the authors investigated whether arginine distribution plays a role in the observed . . .
  

   

  

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